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Article

Activation of c-MET induces a stem-like phenotype in human prostate cancer.

PloS one - 1 Jan 2011

van Leenders Geert J L H, Sookhlall Rajesh, Teubel Wilma J, de Ridder Corrina M A, Reneman Suzanne, Sacchetti Andrea, Vissers Kees J, van Weerden Wytske, Jenster Guido

Abstract excerpt

Prostate cancer consists of secretory cells and a population of immature cells. The function of immature cells and their mutual relation with secretory cells are still poorly understood. Immature cells either have a hierarchical relation to secretory cells (stem cell model) or represent an inducible population emerging upon appropriate stimulation of differentiated cells. Hepatocyte Growth Factor (HGF) receptor...

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Identifiers

PMID: 22110593
DOI: 10.1371/journal.pone.0026753
PMCID: PMC3215704

Genes

MET
HGF
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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