Article
Apoptotic and proliferative status in HPV (+) and HPV (-) inverted papilloma patients. Correlation with local recurrence and clinicopathological variables.
Pathology, research and practice - 15 Jun 2012
Giotakis Evagelos, Gomatos Ilias P, Alevizos Leonidas, Manolopoulos Leonidas, Kataki Agapi, Kandiloros Dimitris, Gorgoulis Vassilis G, Tsimaratou Katerina, Konstantoulakis Manousos M, Yiotakis Ioannis
Abstract excerpt
Inverted papilloma (IP) is a rare sinonasal benign lesion characterized by aggressive biological behavior. Our aim was to evaluate the expression of various proliferation and apoptotic markers and the presence of HPV genotypes in paraffin sections gathered from surgically treated IP patients. Immunohistochemistry for PCNA, bax, cytochrome c and caspase-8 and flow cytometry for the detection of apoptosis, necrosis...
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