Article
p53 mutations and human papillomavirus DNA in oral squamous cell carcinoma: correlation with apoptosis.
British journal of cancer - 1 Aug 1998
Koh J Y, Cho N P, Kong G, Lee J D, Yoon K
Abstract excerpt
Forty-two oral squamous cell carcinomas (SCCs) were analysed for p53 mutations and human papillomavirus (HPV) infection to examine the prevalency of these factors and correlation with apoptotic index (AI; number of apoptotic cells per 100 tumour cells) of the tumour tissue. In polymerase chain reaction (PCR)-Southern blot analysis, HPV DNAs were detected from 22 out of 42 SCCs (52%) with predominance of HPV-16...
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