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Article

Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks?

Hypertension (Dallas, Tex. : 1979) - 1 Jun 2006

Li Jia-Ling, Canham Russell M, Vongpatanasin Wanpen, Leonard David, Auchus Richard J, Victor Ronald G

Abstract excerpt

Sequence variations in the human alpha2 adrenergic receptor genes (ADRA2A and ADRA2C) have been implicated as a cause of hypertension in blacks. Although certain alleles are selectively enriched in blacks, their association with hypertension is based on small convenience samples and has not been evaluated in larger populations. From a stratified random population sample of 3398 individuals (52% blacks), we...

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PMID: 16636200
DOI: 10.1161/01.HYP.0000217972.80731.ef

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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