Article
Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.
Cell - 28 Jun 1991
Chant J, Corrado K, Pringle J R, Herskowitz I
Abstract excerpt
Cells of the yeast S. cerevisiae choose bud sites in an axial or bipolar spatial pattern depending on their cell type. We have identified a gene, BUD5, that resembles BUD1 and BUD2 in being required for both patterns; bud5- mutants also exhibit random budding in all cell types. The BUD5 nucleotide sequence predicts a protein of 538 amino acids that has similarity to the S. cerevisiae CDC25 product, an activator...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Compartmentation
- Cell Cycle
- Cloning, Molecular
- DNA, Fungal
- GTP-Binding Proteins
- Genes, Fungal
- Genetic Complementation Test
- Molecular Sequence Data
- Morphogenesis