Article

The burden of deleterious variants in a non-human primate biomedical model

2019-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Genome sequencing studies of nonhuman primate (NHP) pedigree and population samples are discovering variants on a large and rapidly growing scale. These studies are increasing the utility of several NHP species as model systems for human disease. In particular, by identifying homozygous protein truncating variants (hPTVs) in genes hypothesized to play a role in causing human diseases, it may be...

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Literature Corpus work: c0c20cdd-d3bf-53ba-a00a-f77f493ba325
DOI: 10.1101/784132

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