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Article

Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.

Cancer research - 15 Jul 2012

Garbe James C, Pepin Francois, Pelissier Fanny A, Sputova Klara, Fridriksdottir Agla J, Guo Diana E, Villadsen Rene, Park Morag, Petersen Ole W, Borowsky Alexander D, Stampfer Martha R, Labarge Mark A

Abstract excerpt

Women older than 50 years account for 75% of new breast cancer diagnoses, and the majority of these tumors are of a luminal subtype. Although age-associated changes, including endocrine profiles and alterations within the breast microenvironment, increase cancer risk, an understanding of the cell...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22552289
DOI: 10.1158/0008-5472.CAN-12-0157
PMCID: PMC3399034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22552289-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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