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Article

Association study of copy number variants with brain volume in schizophrenia patients and healthy controls.

Psychiatry research - 30 Dec 2012

Terwisscha van Scheltinga Afke, Bakker Steven, van Haren Neeltje, Buizer-Voskamp Jacobine, Boos Heleen, Vorstman Jacob, Cahn Wiepke, Hulshoff Pol Hilleke, Ophoff Roel, Kahn René

Abstract excerpt

Schizophrenia patients have more copy number variations (CNVs) than healthy controls, and reduced brain volumes. Although this could suggest a causal relationship, we found no association between global CNV burden and three brain volume measures (on a MRI scan) in a sample of 173 schizophrenia patients and 176 healthy controls.

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Identifiers

PMID: 22551941
DOI: 10.1016/j.psychres.2012.04.007

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