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Article

Structural and functional brain alterations revealed by neuroimaging in CNV carriers.

Current opinion in genetics & development - 1 Jun 2021

Moreau Clara A, Ching Christopher Rk, Kumar Kuldeep, Jacquemont Sebastien, Bearden Carrie E

Abstract excerpt

Copy Number Variants (CNVs) are associated with elevated rates of neuropsychiatric disorders. A 'genetics-first' approach, involving the CNV effects on the brain, irrespective of clinical symptomatology, allows investigation of mechanisms underlying neuropsychiatric disorders in the general population. Recent years have seen an increasing number of larger multisite neuroimaging studies investigating the effect of...

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Identifiers

PMID: 33812299
DOI: 10.1016/j.gde.2021.03.002
PMCID: PMC8205978

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