Article
Fecal corticosterone levels in RCAN1 mutant mice.
Comparative medicine - 1 Apr 2012
Rakowski-Anderson Tammy, Wong Helen, Rothermel Beverly, Cain Peter, Lavilla Carmencita, Pullium Jennifer K, Hoeffer Charles
Abstract excerpt
Regulator of calcineurin 1 (RCAN1) is related to the expression of human neurologic disorders such as Down syndrome, Alzheimer disease, and chromosome 21q deletion syndrome. We showed here that RCAN1-knockout mice exhibit reduced innate anxiety as indicated by the elevated-plus maze. To examine whether glucocorticoids contribute to this phenotype, we measured fecal corticosterone in male wildtype and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
