Article
The relevance of the non-canonical PTS1 of peroxisomal catalase.
Biochimica et biophysica acta - 1 Jul 2012
Williams Chris, Bener Aksam Eda, Gunkel Katja, Veenhuis Marten, van der Klei Ida J
Abstract excerpt
Catalase is sorted to peroxisomes via a C-terminal peroxisomal targeting signal 1 (PTS1), which binds to the receptor protein Pex5. Analysis of the C-terminal sequences of peroxisomal catalases from various species indicated that catalase never contains the typical C-terminal PTS1 tripeptide-SKL, but invariably is sorted to peroxisomes via a non-canonical sorting sequence. We analyzed the relevance of the...
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