Article
Pex20p of the yeast Yarrowia lipolytica is required for the oligomerization of thiolase in the cytosol and for its targeting to the peroxisome.
The Journal of cell biology - 27 Jul 1998
Titorenko V I, Smith J J, Szilard R K, Rachubinski R A
Abstract excerpt
Pex mutants are defective in peroxisome assembly. In the pex20-1 mutant strain of the yeast Yarrowia lipolytica, the peroxisomal matrix protein thiolase is mislocalized exclusively to the cytosol, whereas the import of other peroxisomal proteins is unaffected. The PEX20 gene was isolated by funct...
Topics
- Acetyl-CoA C-Acetyltransferase
- Acyl-CoA Oxidase
- Amino Acid Sequence
- Ascomycota
- Base Sequence
- Biological Transport, Active
- Cloning, Molecular
- Cytosol
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Isocitrate Lyase
- Macromolecular Substances
- Microbodies
- Microscopy, Electron
- Models, Biological
- Molecular Sequence Data
- Mutation