Article
Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene.
Biochemical and biophysical research communications - 26 Oct 2001
Ito R, Huang Y, Yao C, Shimozawa N, Suzuki Y, Kondo N, Imanaka T, Usuda N, Ito M
Abstract excerpt
SK32 mutant cells, which were isolated as peroxisome-deficient Chinese hamster ovary (CHO) cells by an advantage of a visible peroxisome form of green fluorescent protein (GFP), were found to suffer from a functional loss of PEX5 gene encoding for PTS1R. The sequence analysis of cDNA indicated that PEX5 gene encoded for the two isoforms composed of 603 amino acids (PTS1RS) and 640 amino acids (PTS1RL). The...
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