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Article

Calcium sensitivity of α-actinin is required for equatorial actin assembly during cytokinesis.

Cell cycle (Georgetown, Tex.) - 15 May 2012

Jayadev Ranjay, Kuk Chun Yin, Low Shyan Huey, Murata-Hori Maki

Abstract excerpt

The actin cross-linking protein, α-actinin, plays a crucial role in mediating furrow ingression during cytokinesis. However, the mechanism by which its dynamics are regulated during this process is poorly understood. Here we have investigated the role of calcium sensitivity of α-actinin in the regulation of its dynamics by generating a functional calcium-insensitive mutant (EFM). GFP-tagged EFM (EFM-GFP)...

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Identifiers

PMID: 22544326
DOI: 10.4161/cc.20277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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