Emergence of Antifungal Resistant Subclades in the Global Predominant Phylogenetic Population of Candida albicans

Abstract excerpt

Invasive candidiasis is the most common human fungal disease among hospitalized patients, and Candida albicans is the predominant pathogen. Considering the large number of infected cases and the limited alternative therapies, the azole-resistance of C. albicans brings a huge clinical threat. Here, our study suggested that antifungal resistance in C. albicans could also be associated with phylogenetic lineages....

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