Article
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder.
PloS one - 1 Jan 2012
Håvik Bjarte, Degenhardt Franziska A, Johansson Stefan, Fernandes Carla P D, Hinney Anke, Scherag André, Lybæk Helle, Djurovic Srdjan, Christoforou Andrea, Ersland Kari M, Giddaluru Sudheer, O'Donovan Michael C, Owen Michael J, Craddock Nick, Mühleisen Thomas W, Mattheisen Manuel, Schimmelmann Benno G, Renner Tobias, Warnke Andreas, Herpertz-Dahlmann Beate, Sinzig Judith, Albayrak Özgür, Rietschel Marcella, Nöthen Markus M, Bramham Clive R, Werge Thomas, Hebebrand Johannes, Haavik Jan, Andreassen Ole A, Cichon Sven, Steen Vidar M, Le Hellard Stéphanie
Abstract excerpt
Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memory and general cognition. We investigated the role of DCLK1 variants in three psychiatric disorders that have neuro-cognitive dysfunctions: schizophrenia (SCZ), bipolar affective disorder (BP) and attention...
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