Article
Predictability of antigenic evolution for H3N2 human influenza A virus.
Genes & genetic systems - 1 Jan 2013
Suzuki Yoshiyuki
Abstract excerpt
Influenza A virus continues to pose a threat to public health. Since this virus can evolve escape mutants rapidly, it is desirable to predict the antigenic evolution for developing effective vaccines. Although empirical methods have been proposed and reported to predict the antigenic evolution more or less accurately, they did not provide much insight into the effects of unobserved mutations and the mechanisms of...
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