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Article

Adenylyl cyclases: expression in the developing rat thalamus and their role in absence epilepsy.

Journal of molecular neuroscience : MN - 1 Sept 2012

Ehling Petra, Kanyshkova Tatyana, Baumann Arnd, Landgraf Peter, Meuth Sven G, Pape Hans-Christian, Budde Thomas

Abstract excerpt

Adenylyl cyclases (ACs) synthesize the second messenger cyclic AMP (cAMP) which influences the function of multiple ion channels. Former studies point to a malfunction of cAMP-dependent ion channel regulation in thalamocortical relay neurons that contribute to the development of the absence epileptic phenotype of a rat genetic model (WAG/Rij). Here, we provide detailed information about the thalamic gene and...

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Source

Identifiers

PMID: 22531884
DOI: 10.1007/s12031-012-9767-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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