Article
An association analysis at 2q36 reveals a new candidate susceptibility gene for juvenile absence epilepsy and/or absence seizures associated with generalized tonic-clonic seizures.
Epilepsia - 1 May 2011
Yalçin Ozlem, Baykan Betül, Ağan Kadriye, Yapici Zuhal, Yalçin Destina, Dizdarer Gülşen, Türkdoğan Dilşad, Ozkara Ciğdem, Unalp Aycan, Uludüz Derya, Gül Günay, Kuşcu Demet, Ayta Semih, Tutkavul Kemal, Comu Sinan, Tatli Burak, Meral Cihan, Bebek Nerses, Cağlayan Server Hande
Abstract excerpt
PURPOSE: To further evaluate the previously shown linkage of absence epilepsy (AE) to 2q36, both in human and WAG/Rij absence rat models, a 160-kb region at 2q36 containing eight genes with expressions in the brain was targeted in a case-control association study involving 205 Turkish patients with AE and 219 controls. METHODS: Haplotype block and case-control association analysis was carried out using HAPLOVIEW...
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