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Article

Antiviral drug resistance and hepatitis B: a continuing public health problem.

Antiviral therapy - 1 Jan 2017

Littlejohn Margaret

Abstract excerpt

The use of selective antiviral therapy has been very successful in controlling HBV replication in individuals, leading to a reduction in disease progression and mortality. However, the use of first-generation therapies, often the only available option in low-resource settings, can result in a high prevalence of drug resistance mutations. Variants selected by antiviral therapies targeting the viral polymerase can...

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PMID: 28504241
DOI: 10.3851/IMP3176

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