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Article

Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes.

Mutation research - 1 Jun 2012

Slattery Martha L, Lundgreen Abbie, Welbourn Bill, Wolff Roger K, Corcoran Christopher

Abstract excerpt

Pro-oxidant and anti-oxidant genetic and lifestyle factors can contribute to an individual's level of oxidative stress. We hypothesize that diet, lifestyle and genetic factors work together to influence colon and rectal cancer through an oxidative balance mechanism. We evaluated nine markers for eosinophil peroxidase (EPX), two for myeloperoxidase (MPO), four for hypoxia-inducible factor-1A (HIFIA), and 16 for...

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Source

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Identifiers

PMID: 22531693
DOI: 10.1016/j.mrfmmm.2012.04.002
PMCID: PMC3372651

Genes

EPX
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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