Article
A population-based association study of SNPs of GSTP1, MnSOD, GPX2 and Barrett's esophagus and esophageal adenocarcinoma.
Carcinogenesis - 1 Jun 2007
Murphy Seamus J, Hughes Anne E, Patterson Chris C, Anderson Lesley A, Watson R G Peter, Johnston Brian T, Comber Harry, McGuigan Jim, Reynolds John V, Murray Liam J
Abstract excerpt
Oxidative stress appears to be important in the pathogenesis of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC). Single-nucleotide polymorphisms (SNPs) of antioxidant enzyme genes may play a part in determining individual susceptibility to these diseases. The Factors Influencing the Barrett's Adenocarcinoma Relationship (FINBAR) study is a population-based, case-control study of BE and EAC in...
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