Article
Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology
22 Oct 2019
Abstract excerpt
Chronic inflammation is an established risk factor for colorectal cancer. To study reactive products of gut inflammation and redox signaling on colorectal cancer development, we used untargeted adductomics to detect adduct features in prediagnostic serum from the EPIC Italy cohort. We focused on modifications to Cys34 in human serum albumin, which is responsible for scavenging small reactive electrophiles that...
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