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Article

Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents.

Psychiatric genetics - 1 Oct 2012

Schirmbeck Frederike, Nieratschker Vanessa, Frank Josef, Englisch Susanne, Rausch Franziska, Meyer-Lindenberg Andreas, Rietschel Marcella, Zink Mathias

Abstract excerpt

BACKGROUND: A large subgroup of schizophrenic patients develops obsessive-compulsive symptoms (OCS) during treatment with second-generation antipsychotics (SGA). A genetic risk factor for these secondary OCS was recently described in the gene SLC1A1 encoding the neuronal glutamate transporter excitatory amino acid carrier 1. The aim of this study was to replicate these findings in a European sample. METHODS: A...

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PMID: 22531293
DOI: 10.1097/YPG.0b013e328353fbee

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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