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Article

Three nth homologs are all required for efficient repair of spontaneous DNA damage in Deinococcus radiodurans.

Extremophiles : life under extreme conditions - 1 May 2012

Hua Xiaoting, Xu Xin, Li Mingfeng, Wang Chao, Tian Bing, Hua Yuejin

Abstract excerpt

Deinococcus radiodurans is a bacterium that can survive extreme DNA damage. To understand the role of endonuclease III (Nth) in oxidative repair and mutagenesis, we constructed nth single, double and triple mutants. The nth mutants showed no significant difference with wild type in both IR resistance and H(2)O(2) resistance. We characterized these strains with regard to mutation rates and mutation spectrum using...

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PMID: 22527041
DOI: 10.1007/s00792-012-0447-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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