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Article

Do genetic variants in the SPINK1 gene affect the level of serum PSTI?

Journal of gastroenterology - 1 Nov 2012

Kume Kiyoshi, Masamune Atsushi, Ariga Hiroyuki, Hayashi Shintaro, Takikawa Tetsuya, Miura Shin, Suzuki Noriaki, Kikuta Kazuhiro, Hamada Shin, Hirota Morihisa, Kanno Atsushi, Shimosegawa Tooru

Abstract excerpt

BACKGROUND: The serine protease inhibitor Kazal type 1 (SPINK1), also known as pancreatic secretory trypsin inhibitor (PSTI), is a peptide secreted by pancreatic acinar cells. Genetic studies have shown an association between SPINK1 gene variants and chronic pancreatitis or recurrent acute pancreatitis. The aim of this study was to clarify whether the SPINK1 variants affect the level of serum PSTI. METHODS: One...

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Source

Identifiers

PMID: 22526274
DOI: 10.1007/s00535-012-0590-3

Genes

SPINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Do genetic variants in the SPINK1 gene affect the level of serum PSTI?PMID 22526274Read ↗

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