Correlation between gene polymorphisms of CYP1A1, GSTP1, ERCC2, XRCC1, and XRCC3 and susceptibility to lung cancer.

doi:10.4238/gmr15048813

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Article

Correlation between gene polymorphisms of CYP1A1, GSTP1, ERCC2, XRCC1, and XRCC3 and susceptibility to lung cancer.

Genetics and molecular research : GMR - 3 Nov 2016

Liu H X, Li J, Ye B G

Abstract excerpt

Lung cancer is a common malignant tumor that is characterized by high morbidity and poor prognosis. Studies suggest that an individual's genetic background affects the risk of developing lung cancer. Therefore, we investigated the relationship between gene polymorphisms and susceptibility to lung cancer. We recruited 308 primary lung cancer patients as subjects and 253 healthy adults as controls. After extraction...

Topics

Case-Control Studies
Cytochrome P-450 CYP1A1
DNA Repair
DNA-Binding Proteins
Female
Genetic Predisposition to Disease
Glutathione S-Transferase pi
Humans
Lung Neoplasms
Male
Middle Aged
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide
X-ray Repair Cross Complementing Protein 1
Xeroderma Pigmentosum Group D Protein

Source

Open in PubMed

Identifiers

PMID: 27819744
DOI: 10.4238/gmr15048813

Genes

ERCC2
GSTP1
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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