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Article

Developmental regulation of chromatin conformation by Hox proteins in Drosophila.

Cell reports - 19 Apr 2012

Agelopoulos Marios, McKay Daniel J, Mann Richard S

Abstract excerpt

We present a strategy to examine the chromatin conformation of individual loci in specific cell types during Drosophila embryogenesis. Regulatory DNA is tagged with binding sites (lacO) for LacI, which is used to immunoprecipitate the tagged chromatin from specific cell types. We applied this approach to Distalless (Dll), a gene required for limb development in Drosophila. We show that the local chromatin...

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Share to Chromatin
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Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Homeodomain Proteins

Share to Promoter Regions, Genetic

Share to Regulatory Sequences, Nucleic Acid

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Identifiers

PMID: 22523743
DOI: 10.1016/j.celrep.2012.03.003
PMCID: PMC3329935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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