Proximodistal axis formation in the Drosophila leg: subdivision into proximal and distal domains by Homothorax and Distal-less.

doi:10.1242/dev.126.1.109

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Article

Proximodistal axis formation in the Drosophila leg: subdivision into proximal and distal domains by Homothorax and Distal-less.

Development (Cambridge, England) - 1 Jan 1999

Wu J, Cohen S M

Abstract excerpt

The developing legs of Drosophila are subdivided into proximal and distal domains by the activity of the homeodomain proteins Homothorax (Hth) and Distal-less (Dll). The expression domains of Dll and Hth are initially reciprocal. Wingless and Dpp define both domains by activating Dll and by repre...

Topics

Animals
Body Patterning
Drosophila
Drosophila Proteins
Extremities
Gene Expression Regulation, Developmental
Homeodomain Proteins
Insect Proteins
Larva
Mutation
Proto-Oncogene Proteins
Transcription Factors
Wnt1 Protein

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