Article
Association between single-nucleotide polymorphisms on chromosome 1p22 and 20q12 and nonsyndromic cleft lip with or without cleft palate: new data in Han Chinese and meta-analysis.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2012
Huang Enmin, Cheng Hongqiu, Xu Mingyan, Shu Shenyou, Tang Shijie
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation associated with genetic and environmental risk factors. A recent genome-wide association study identified two novel susceptibility loci on chromosomes 1p22 and 20q12; however, conflicting results, especially for 1p22, have been reported in Han Chinese population. The aims of this study were to replicate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.