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Article

DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma.

Ophthalmic genetics - 1 Apr 2018

Burdon Kathryn P, Awadalla Mona S, Mitchell Paul, Wang Jie Jin, White Andrew, Keane Miriam C, Souzeau Emmanuelle, Graham Stuart L, Goldberg Ivan, Healey Paul R, Landers John, Mills Richard A D, Best Stephen, Hewitt Alex W, Sharma Shiwani, Craig Jamie E

Abstract excerpt

PURPOSE: Recent genome-wide association studies reported strong association of genetic variation at the CDKN2B/CDKN2B-AS1 locus on 9p21 with normal-tension glaucoma (NTG) in multiple populations. The mechanism by which this locus causes disease remains to be elucidated. We investigated the association of DNA methylation of CpG islands at this locus with NTG. METHODS: We conducted a retrospective case-control...

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Share to Chromosomes, Human, Pair 9
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p15

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Identifiers

PMID: 29265947
DOI: 10.1080/13816810.2017.1413659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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