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Article

Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans.

Biological psychiatry - 15 Oct 2012

Han Shizhong, Yang Bao-Zhu, Kranzler Henry R, Oslin David, Anton Raymond, Farrer Lindsay A, Gelernter Joel

Abstract excerpt

BACKGROUND: A genetic contribution to cannabis dependence (CaD) has been established but susceptibility genes for CaD remain largely unknown. METHODS: We employed a multistage design to identify genetic variants underlying CaD. We first performed a genome-wide linkage scan for CaD in 384 African American (AA) and 354 European American families ascertained for genetic studies of cocaine and opioid dependence. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22520967
DOI: 10.1016/j.biopsych.2012.02.038
PMCID: PMC3699339

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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