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Article

Regulation of Helicobacter pylori adherence by gene conversion

23 Apr 2012

Abstract excerpt

Genetic diversification of Helicobacter pylori adhesin genes may allow adaptation of adherence properties to facilitate persistence despite host defences. The sabA gene encodes an adhesin that binds sialyl-Lewis antigens on inflamed gastric tissue. We found variability in the copy number and locus of the sabA gene and the closely related sabB and omp27 genes due to gene conversion among 51 North American...

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PMID: 22519812
DOI: 10.1111/j.1365-2958.2012.08073.x

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