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Article

Determinants of the regulation of Helicobacter pylori adhesins include repeat sequences in both promoter and coding regions as well as the two-component system ArsRS.

Journal of medical microbiology - 1 Jun 2017

Acio-Pizzarello Catherine R, Acio Abigail A, Choi Edward J, Bond Kimberly, Kim June, Kenan Anna C, Chen Jiajia, Forsyth Mark H

Abstract excerpt

PURPOSE: We investigated the transcription of adhesin-encoding genes sabA, hopZ and labA in Helicobacter pylori strain J99. Each possesses a repeating homopolymeric nucleotide tract within their promoter regions, and sabA and hopZ possess repeats within their 5' coding regions. METHODOLOGY: We altered the repeat lengths associated with the adhesin genes and quantified mRNA levels by real-time quantitative PCR....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28598306
DOI: 10.1099/jmm.0.000491

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