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Interaction Between Host Gastric Sialyl-Lewis X and H. pylori SabA Enhances H. pylori Density in Patients Lacking Gastric Lewis B Antigen

1 Jan 2006

Abstract excerpt

OBJECTIVES: We tested whether the interaction between host gastric Le(x) antigen and the SabA protein of H. pylori determined gastric colonization density. METHODS: A total of 145 H. pylori-infected patients were assessed for their bacterial density and gastric Le(b) and sialyl-Le(x) expression. Their corresponding H. pylori isolates were tested for babA2 and sabA genotype by PCR. The sabA-genopositive PCR...

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PMID: 16405531
DOI: 10.1111/j.1572-0241.2006.00358.x

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