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Article

Association of XPC polymorphisms with susceptibility and clinical outcome to chemotherapy in breast cancer patients.

Cancer science - 1 Jul 2012

Yang Xiuli, Liu Duo, Wu Huizhe, Kang Hui, Pang Hao, Huang Desheng, Sha Xianzheng, Wang Enhua, Wang Zhe, Wei Minjie

Abstract excerpt

The aim of the current study was to evaluate the relation between xeroderma pigmentosum complementation group C (XPC) polymorphisms and susceptibility to breast cancer (BC), the development and progression of disease, and response to different individualized drug treatments. We investigated two polymorphisms in XPC Ala499Val and Lys939Gln using PCR-RFLP assays including 618 cases and 622 controls. The frequency...

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Source

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Identifiers

PMID: 22519360
DOI: 10.1111/j.1349-7006.2012.02312.x
PMCID: PMC7659375

Genes

XPC
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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