Article
Xeroderma pigmentosum complementation group C genotypes/diplotypes play no independent or interaction role with polycyclic aromatic hydrocarbons-DNA adducts for breast cancer risk.
European journal of cancer (Oxford, England : 1990) - 1 Mar 2008
Shen Jing, Gammon Marilie D, Terry Mary Beth, Teitelbaum Susan L, Eng Sybil M, Neugut Alfred I, Santella Regina M
Abstract excerpt
Xeroderma pigmentosum complementation group C (XPC) is an important DNA nuclear excision repair (NER) gene that recognises the damage caused by a variety of bulky DNA adducts. We evaluated the association of two common non-synonymous polymorphisms in XPC (Ala499Val and Lys939Gln) with breast cancer risk in the Long Island Breast Cancer Study Project (LIBCSP), a population-based case-control study. Genotyping of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.