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Antagonistic modulation of gliomagenesis by <i>Pax6</i> and <i>Olig2</i> in PDGF‐induced oligodendroglioma

19 Apr 2012

Abstract excerpt

Gliomas are aggressive tumors of the central nervous system originating from proliferating neural cells. Regulators of neural stem or progenitor cells biology may thus influence aspects of brain tumorigenesis, such as the maintenance of tumor-propagating potential. We investigated the role of Pax6, a neurogenic transcription factor already suggested as a positive prognostic marker for human gliomas, in a...

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PMID: 22514120
DOI: 10.1002/ijc.27606

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