Article
The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker.
Neuron - 22 Dec 2005
Lear Bridget C, Lin Jui-Ming, Keath J Russel, McGill Jermaine J, Raman Indira M, Allada Ravi
Abstract excerpt
Circadian clocks consist of transcriptional feedback loops housed in interdependent pacemaker neurons. Yet little is known about the neuronal output components essential for rhythmic behavior. Drosophila mutants of a putative ion channel, narrow abdomen (na), exhibit poor circadian rhythms and suppressed daylight activity. We find that NA is expressed in pacemaker neurons and induced expression within circadian...
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