Article

VarSAn: Associating pathways with a set of genomic variants using network analysis

2020-12-23

Abstract excerpt

<h4>ABSTRACT</h4> There is a pressing need today to mechanistically interpret sets of genomic variants associated with diseases. Here we present a tool called ‘VarSAn’ that uses a network analysis algorithm to identify pathways relevant to a given set of variants. VarSAn analyzes a configurable network whose nodes represent variants, genes and pathways, using a Random Walk with Restarts algorithm to rank pathways...

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Literature Corpus work: ff779262-5428-5fb8-becf-87347f14ad12
DOI: 10.1101/2020.12.22.424077

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