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Article

Colorectal carcinoma occurring via the adenoma-carcinoma pathway in patients with serrated polyposis syndrome.

Journal of gastroenterology - 1 Apr 2022

Nakamura Fumika, Sato Yasushi, Okamoto Koichi, Fujino Yasuteru, Mitsui Yasuhiro, Kagemoto Kaizo, Kawaguchi Tomoyuki, Miyamoto Hiroshi, Muguruma Naoki, Sonoda Tomoko, Tsuneyama Koichi, Takayama Tetsuji

Abstract excerpt

BACKGROUND: Although serrated polyposis syndrome (SPS) is associated with an increased colorectal cancer (CRC) risk, the carcinogenic mechanisms remain unknown. We investigated clinicopathological characteristics and genetic abnormalities in colorectal polyps and CRC to elucidate carcinogenic mechanisms in SPS. METHODS: We retrospectively analyzed clinicopathological features of colorectal polyps in 44 SPS...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35194694
DOI: 10.1007/s00535-022-01858-8

Genes

HP
APC
BRAF
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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