Article
Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study.
International journal of colorectal disease - 1 Jun 2010
Buchanan Daniel D, Sweet Kevin, Drini Musa, Jenkins Mark A, Win Aung Ko, Gattas Michael, Walsh Michael D, Clendenning Mark, McKeone Diane, Walters Rhiannon, Roberts Aedan, Young Alasdair, Hampel Heather, Hopper John L, Goldblatt Jack, George Jill, Suthers Graeme K, Phillips Kerry, Young Graeme P, Chow Elizabeth, Parry Susan, Woodall Sonja, Tucker Kathy, Muir Amanda, Field Michael, Greening Sian, Gallinger Steven, Green Jane, Woods Michael O, Spaetgens Renee, de la Chapelle Albert, Macrae Finlay, Walker Neal I, Jass Jeremy R, Young Joanne P
Abstract excerpt
OBJECTIVE: Hyperplastic polyposis is a colonic polyposis condition of unknown aetiology. The purpose of this study was to examine the spectrum of phenotypic variation in patients with multiple serrated polyps as a basis for gene discovery. METHODS: One hundred and twenty-six patients with multiple (> or = 5) serrated polyps were recruited to the study. Polyp counts were extracted from histology and colonoscopy...
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