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Article

Double‐hit <scp>BCL</scp>2/<scp>MYC</scp> translocations in a consecutive cohort of patients with large B‐cell lymphoma – a single centre's experience

17 Apr 2012

Abstract excerpt

Concurrent BCL2 and MYC translocations, so called double hit (DH), are a rare finding in large B-cell lymphoma (LBCL). Based on data from retrospective series, DH has been correlated with aggressive clinical behaviour and poor outcome. We conducted a consecutive study of DH incidence and correlation with pathologic and clinical characteristics, including response to Rituximab-containing chemotherapy and survival,...

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PMID: 22510149
DOI: 10.1111/j.1600-0609.2012.01787.x

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