<scp>MYC</scp> translocation partner gene determines survival of patients with large B‐cell lymphoma with <scp>MYC</scp>‐ or double‐hit <scp>MYC</scp>/<scp>BCL</scp>2 translocations

Abstract excerpt

In large B-cell lymphoma (LBCL) MYC- and MYC/BCL2 double-hit (DH) translocations have been associated with inferior survival. We hypothesised that the negative prognostic impact of MYC translocation was determined by an immunoglobulin MYC translocation partner gene (IG-MYC), as opposed to a non-immunoglobulin partner gene (nonIG-MYC). In a prospective, unselected cohort of 237 LBCL patients MYC and BCL2...

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