Frequency of IL28B rs12979860 single-nucleotide polymorphism alleles in newborn infants and in patients with chronic hepatitis C in Morocco.

doi:10.1089/gtmb.2011.0353

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Frequency of IL28B rs12979860 single-nucleotide polymorphism alleles in newborn infants and in patients with chronic hepatitis C in Morocco.

Genetic testing and molecular biomarkers - 1 Aug 2012

Tajir Mariam, Elmachad Mustapha, Kabbaj Nawal, Laarabi Fatima Zahra, Barkat Amina, Amrani Naima, Sefiani Abdelaziz

Abstract excerpt

BACKGROUND: Epidemiological and experimental evidence support the role of host genetics in treatment response and viral clearance in chronic hepatitis C (CHC). Recently, the CC genotype of IL28B single-nucleotide polymorphism (SNP) rs12979860 has been associated with spontaneous viral clearance and a better treatment response. The distribution of this polymorphism varies according to populations. Frequency of...

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PMID: 22509814
DOI: 10.1089/gtmb.2011.0353

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