Article
Effects of NKG2D haplotypes on the cell-surface expression of NKG2D protein on natural killer and CD8 T cells of peripheral blood among atomic-bomb survivors.
Human immunology - 1 Jun 2012
Imai Kazue, Hayashi Tomonori, Yamaoka Mika, Kajimura Junko, Yoshida Kengo, Kusunoki Yoichiro, Nakachi Kei
Abstract excerpt
NKG2D is a primary activating receptor that triggers cell-mediated cytotoxicity in NK cells against tumor and virus-infected cells. We previously identified the NKG2D haplotypes in the natural killer gene complex region on chromosome 12p. Two major haplotype alleles, LNK1 and HNK1, were closely r...
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