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Article

Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.

Journal of biomedicine & biotechnology - 1 Jan 2012

Silk Kathryn M, Leishman Alison J, Nishimoto Kevin P, Reddy Anita, Fairchild Paul J

Abstract excerpt

While human embryonic stem cells (hESCs) may one day facilitate the treatment of degenerative diseases requiring cell replacement therapy, the success of regenerative medicine is predicated on overcoming the rejection of replacement tissues. Given the role played by dendritic cells (DCs) in the establishment of immunological tolerance, we have proposed that DC, rendered tolerogenic during their differentiation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22505805
DOI: 10.1155/2012/172420
PMCID: PMC3303870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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