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Article

Tacrolimus dosing in Chinese renal transplant patients is related to MDR1 gene C3435T polymorphisms.

Transplantation proceedings - 1 Nov 2006

Li D, Gui R, Li Jin, Huang Z, Nie Xinmin

Abstract excerpt

Tacrolimus is an immunosuppressive drug with narrow therapeutic range and wide interindividual variations in its pharmacokinetics. P-glycoprotein (P-gp) plays an important role in the absorption metabolism of tacrolimus. The polymorphism C3435T of MDR1, the gene coding P-gp, may influence the expression and activity of P-gp. The aim of this study was to evaluate whether C3435T polymorphism was associated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17112846
DOI: 10.1016/j.transproceed.2006.08.089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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