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Article

Clonal competition with alternating dominance in multiple myeloma

13 Apr 2012

Abstract excerpt

Emerging evidence indicates that tumors can follow several evolutionary paths over a patient's disease course. With the use of serial genomic analysis of samples collected at different points during the disease course of 28 patients with multiple myeloma, we found that the genomes of standard-risk patients show few changes over time, whereas those of cytogenetically high-risk patients show significantly more...

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Share to Monoclonal and Polyclonal Antibodies Research
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PMID: 22498740
DOI: 10.1182/blood-2012-01-405985

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