Article
Comparison of joining and constant κ-light chain regions in different cattle breeds.
Animal genetics - 1 Dec 2012
Stein S K, Diesterbeck U S, Aboelhassan D M, Czerny C-P
Abstract excerpt
A comparative transcription analysis of Ig κ-light chains (IGK) of the cattle breeds Holstein Friesian (HF), German Black Pied (GBP), German Simmental (GS) and Aubrac (A) revealed three alleles coding for two putative allotypic variants of IGKC. The amino acid residues p.Asp100Asn and p.Thr116Ala were located at the outer edge of the constant domain as demonstrated by homology-based modelling. Alleles were...
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